Considerations To Know About ceesdekker
Considerations To Know About ceesdekker
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Spatial construction facilitates cooperation in the social Problem: empirical evidence from a bacterial Neighborhood
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
‘It absolutely was only a issue of choosing up a book on mobile biology and starting to study. I had originate from a entire world of ultra-high vacuums, cryostats and quantum phenomena, and now I had been Doing work at room temperature with molecular biology kits.
I'm able to hardly envision how I, as a geneticist, would have the ability to learn essential physics, not to mention compete at the best. How did you go over it?
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first at any time examine from the dynamics DNA supercoils and the invention of supercoil hopping
Our analysis ranges in the biophysics of DNA to artificial cells and over and above. Please take a look beneath at the spectrum of our latest assignments.
What distinguishes biology from chemistry is usually that these factors alongside one another make up a dwelling process. The key of explained daily life, I believe, lies inside the interactions, the interplay of those molecules. The massive dilemma about the origin of everyday living remains unanswered. How did we ever evolve from straightforward molecules in to the extremely intricate techniques we see these days? We do not know. I need to work on These types of major, open up concerns.’
Nanopores stand for a sublime and multipurpose Software to evaluate one molecules. We exploration novel detection modes with good-point out nanopores and many tips on how to evaluate proteins with nanopores. Initiatives encompass the next:
2003, demonstrated the first biosensors made outside of a carbon nanotube; solved the framework and mechanism of DNA repair proteins; and discovery of a new system for fabricating good-condition nanopores for DNA translocation
Dekker started off his analysis on single carbon nanotubes in 1993 when he build a whole new line of analysis to check electrical transportation via one natural molecules between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was attained in a collaboration While using the group of Nobel laureate Richard Smalley. STM and nanolithography procedures have been used to display that these nanotubes are quantum wires at the single-molecule amount, with exceptional Actual physical Homes.
Since 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his exploration has focused on finding out chromatin construction and mobile division with germs on chip, though he is additionally seeking to eventually build artificial cells from The underside up.
Cees Dekker is Distinguished University Professor at TU Delft. Skilled like a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes while in the nineties. Considering that 2000, he moved to solitary-molecule ceesdekker biophysics and nanobiology. His recent investigation focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) building a dwelling artificial cell from lifeless molecules. Dekker is surely an elected member in the KNAW and fellow towards the APS as well as IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style and design in 2005. (nl)